Daniil Medvedev on Sunday admitted he would rather be playing at the mixed teams United Cup than the Adelaide International, but the Russian intends to make the most of the season-opening event.
The Monte Carlo-based world number seven and his compatriots are unable to compete in the ATP-WTA United Cup in response to the invasion of Ukraine.
Medvedev, a finalist at the last two Australian Opens, will start against Italian Lorenzo Sonego.
Since defeating Djokovic for the 2021 US Open title, Medvedev has been beaten three times by the Serb, who is back in Australia after being deported a year ago for trying to enter without a Covid vaccination exemption.
With the rules now relaxed, the 35-year-old is competing in Adelaide and is free to pursue a possible 10th title at Melbourne Park this month.